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SMILES: CN(C)c1ncc(C(N)=O)c(Nc2ccc(CC(=O)NCC(C)(C)C)cc2)n1

InChI Key: InChIKey=XTPXDKGSBIGQPN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50493957   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50493957
PNG
(CHEMBL2442461)
Show SMILES CN(C)c1ncc(C(N)=O)c(Nc2ccc(CC(=O)NCC(C)(C)C)cc2)n1
Show InChI InChI=1S/C20H28N6O2/c1-20(2,3)12-23-16(27)10-13-6-8-14(9-7-13)24-18-15(17(21)28)11-22-19(25-18)26(4)5/h6-9,11H,10,12H2,1-5H3,(H2,21,28)(H,23,27)(H,22,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human PDE4B using cAMP as substrate after 30 mins

Bioorg Med Chem 21: 7025-37 (2013)


Article DOI: 10.1016/j.bmc.2013.09.013
BindingDB Entry DOI: 10.7270/Q2DZ0C84
More data for this
Ligand-Target Pair