BDBM50495086 CHEMBL3098697

SMILES: ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NC1CCCC1

InChI Key: InChIKey=NLFOGCNUIMUZSG-GJZGRUSLSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50495086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50495086 (CHEMBL3098697) Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H32N4O5/c24-16-12-6-10-14(21-16)19(27)22-15(9-2-1-3-11-17(25)23-28)18(26)20-13-7-4-5-8-13/h13-15,28H,1-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysis				Bioorg Med Chem Lett 24: 61-4 (2014) Article DOI: 10.1016/j.bmcl.2013.11.072 BindingDB Entry DOI: 10.7270/Q21839GT
					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50495086 (CHEMBL3098697) Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H32N4O5/c24-16-12-6-10-14(21-16)19(27)22-15(9-2-1-3-11-17(25)23-28)18(26)20-13-7-4-5-8-13/h13-15,28H,1-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC3/NCOR2 using RHKK(Ac) as substrate by fluorimetric analysis				Bioorg Med Chem Lett 24: 61-4 (2014) Article DOI: 10.1016/j.bmcl.2013.11.072 BindingDB Entry DOI: 10.7270/Q21839GT
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 2 (Homo sapiens (Human))	BDBM50495086 (CHEMBL3098697) Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H32N4O5/c24-16-12-6-10-14(21-16)19(27)22-15(9-2-1-3-11-17(25)23-28)18(26)20-13-7-4-5-8-13/h13-15,28H,1-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysis				Bioorg Med Chem Lett 24: 61-4 (2014) Article DOI: 10.1016/j.bmcl.2013.11.072 BindingDB Entry DOI: 10.7270/Q21839GT
					More data for this Ligand-Target Pair
Histone deacetylase 10 (Homo sapiens (Human))	BDBM50495086 (CHEMBL3098697) Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H32N4O5/c24-16-12-6-10-14(21-16)19(27)22-15(9-2-1-3-11-17(25)23-28)18(26)20-13-7-4-5-8-13/h13-15,28H,1-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysis				Bioorg Med Chem Lett 24: 61-4 (2014) Article DOI: 10.1016/j.bmcl.2013.11.072 BindingDB Entry DOI: 10.7270/Q21839GT
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50495086 (CHEMBL3098697) Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H32N4O5/c24-16-12-6-10-14(21-16)19(27)22-15(9-2-1-3-11-17(25)23-28)18(26)20-13-7-4-5-8-13/h13-15,28H,1-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysis				Bioorg Med Chem Lett 24: 61-4 (2014) Article DOI: 10.1016/j.bmcl.2013.11.072 BindingDB Entry DOI: 10.7270/Q21839GT
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50495086 (CHEMBL3098697) Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H32N4O5/c24-16-12-6-10-14(21-16)19(27)22-15(9-2-1-3-11-17(25)23-28)18(26)20-13-7-4-5-8-13/h13-15,28H,1-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysis				Bioorg Med Chem Lett 24: 61-4 (2014) Article DOI: 10.1016/j.bmcl.2013.11.072 BindingDB Entry DOI: 10.7270/Q21839GT
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50495086 (CHEMBL3098697) Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCCC(=O)N1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H32N4O5/c24-16-12-6-10-14(21-16)19(27)22-15(9-2-1-3-11-17(25)23-28)18(26)20-13-7-4-5-8-13/h13-15,28H,1-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysis				Bioorg Med Chem Lett 24: 61-4 (2014) Article DOI: 10.1016/j.bmcl.2013.11.072 BindingDB Entry DOI: 10.7270/Q21839GT
					More data for this Ligand-Target Pair