null

SMILES: Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCN(CCCCc2ccccc2)CC1

InChI Key: InChIKey=LJWJIAGUUHPNOE-DEOSSOPVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50495232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50495232 (CHEMBL3104100) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCN(CCCCc2ccccc2)CC1 |r| Show InChI InChI=1S/C25H35N3O2/c1-19-16-22(29)17-20(2)23(19)18-24(26)25(30)28-14-12-27(13-15-28)11-7-6-10-21-8-4-3-5-9-21/h3-5,8-9,16-17,24,29H,6-7,10-15,18,26H2,1-2H3/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes after 1 hr by liquid scintillation counting analysis				Bioorg Med Chem Lett 24: 548-51 (2014) Article DOI: 10.1016/j.bmcl.2013.12.021 BindingDB Entry DOI: 10.7270/Q2TH8QNG
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50495232 (CHEMBL3104100) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCN(CCCCc2ccccc2)CC1 |r| Show InChI InChI=1S/C25H35N3O2/c1-19-16-22(29)17-20(2)23(19)18-24(26)25(30)28-14-12-27(13-15-28)11-7-6-10-21-8-4-3-5-9-21/h3-5,8-9,16-17,24,29H,6-7,10-15,18,26H2,1-2H3/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cell membranes after 1 hr by liquid scintillation counting analy...				Bioorg Med Chem Lett 24: 548-51 (2014) Article DOI: 10.1016/j.bmcl.2013.12.021 BindingDB Entry DOI: 10.7270/Q2TH8QNG
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50495232 (CHEMBL3104100) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCN(CCCCc2ccccc2)CC1 |r| Show InChI InChI=1S/C25H35N3O2/c1-19-16-22(29)17-20(2)23(19)18-24(26)25(30)28-14-12-27(13-15-28)11-7-6-10-21-8-4-3-5-9-21/h3-5,8-9,16-17,24,29H,6-7,10-15,18,26H2,1-2H3/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting analys...				Bioorg Med Chem Lett 24: 548-51 (2014) Article DOI: 10.1016/j.bmcl.2013.12.021 BindingDB Entry DOI: 10.7270/Q2TH8QNG
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50495232 (CHEMBL3104100) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCN(CCCCc2ccccc2)CC1 |r| Show InChI InChI=1S/C25H35N3O2/c1-19-16-22(29)17-20(2)23(19)18-24(26)25(30)28-14-12-27(13-15-28)11-7-6-10-21-8-4-3-5-9-21/h3-5,8-9,16-17,24,29H,6-7,10-15,18,26H2,1-2H3/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Agonist activity at rat mu opioid receptor expressed in rat C6 cells assessed as stimulation of [35S]-GTPgammaS binding after 1 hr by liquid scintill...				Bioorg Med Chem Lett 24: 548-51 (2014) Article DOI: 10.1016/j.bmcl.2013.12.021 BindingDB Entry DOI: 10.7270/Q2TH8QNG
					More data for this Ligand-Target Pair