BindingDB logo
myBDB logout

null

SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CS)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O

InChI Key: InChIKey=BTFNJNJXRODXRT-ILRJEIQWSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50495422   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon-like peptide 1 receptor


(Homo sapiens (Human))		BDBM50495422
PNG
(CHEMBL3110306)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CS)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
Show InChI InChI=1S/C145H217N39O45S/c1-16-73(10)116(142(227)162-76(13)121(206)169-99(55-82-58-154-87-33-24-23-32-85(82)87)131(216)171-95(51-70(4)5)132(217)181-114(71(6)7)140(225)168-89(34-25-26-48-146)124(209)156-61-106(192)163-88(119(149)204)35-27-49-153-145(150)151)183-133(218)97(52-79-28-19-17-20-29-79)172-128(213)93(43-47-112(200)201)167-139(224)104(67-230)179-122(207)75(12)160-120(205)74(11)161-127(212)92(40-44-105(148)191)165-108(194)62-157-126(211)91(42-46-111(198)199)166-129(214)94(50-69(2)3)170-130(215)96(54-81-36-38-84(190)39-37-81)173-136(221)101(64-185)176-138(223)103(66-187)177-141(226)115(72(8)9)182-135(220)100(57-113(202)203)174-137(222)102(65-186)178-144(229)118(78(15)189)184-134(219)98(53-80-30-21-18-22-31-80)175-143(228)117(77(14)188)180-109(195)63-158-125(210)90(41-45-110(196)197)164-107(193)60-155-123(208)86(147)56-83-59-152-68-159-83/h17-24,28-33,36-39,58-59,68-78,86,88-104,114-118,154,185-190,230H,16,25-27,34-35,40-57,60-67,146-147H2,1-15H3,(H2,148,191)(H2,149,204)(H,152,159)(H,155,208)(H,156,209)(H,157,211)(H,158,210)(H,160,205)(H,161,212)(H,162,227)(H,163,192)(H,164,193)(H,165,194)(H,166,214)(H,167,224)(H,168,225)(H,169,206)(H,170,215)(H,171,216)(H,172,213)(H,173,221)(H,174,222)(H,175,228)(H,176,223)(H,177,226)(H,178,229)(H,179,207)(H,180,195)(H,181,217)(H,182,220)(H,183,218)(H,184,219)(H,196,197)(H,198,199)(H,200,201)(H,202,203)(H4,150,151,153)/t73-,74-,75-,76-,77+,78+,86-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,114-,115-,116-,117-,118-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 0.00300n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Activation of human GLP-1 receptor overexpressed in HEK293 cells assessed as cAMP accumulation after 20 mins by HTRF assay

J Med Chem 56: 9955-68 (2013)


Article DOI: 10.1021/jm4017448
BindingDB Entry DOI: 10.7270/Q2H41VDR
More data for this
Ligand-Target Pair