null

SMILES: COc1ccc(cc1)-c1ccccc1N1CCN(CCOCCC(=O)NCc2ccc(F)nc2)CC1

InChI Key: InChIKey=MDEUQQCHGQKBNS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50495573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50495573 (CHEMBL3113594) Show SMILES COc1ccc(cc1)-c1ccccc1N1CCN(CCOCCC(=O)NCc2ccc(F)nc2)CC1 Show InChI InChI=1S/C28H33FN4O3/c1-35-24-9-7-23(8-10-24)25-4-2-3-5-26(25)33-15-13-32(14-16-33)17-19-36-18-12-28(34)31-21-22-6-11-27(29)30-20-22/h2-11,20H,12-19,21H2,1H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL					Assay Description Displacement of [3H]5-CT from human 5HT7 receptor transfected in HEK293 cells after 60 mins				Bioorg Med Chem 22: 1736-50 (2014) Article DOI: 10.1016/j.bmc.2014.01.016 BindingDB Entry DOI: 10.7270/Q2JW8HV0
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50495573 (CHEMBL3113594) Show SMILES COc1ccc(cc1)-c1ccccc1N1CCN(CCOCCC(=O)NCc2ccc(F)nc2)CC1 Show InChI InChI=1S/C28H33FN4O3/c1-35-24-9-7-23(8-10-24)25-4-2-3-5-26(25)33-15-13-32(14-16-33)17-19-36-18-12-28(34)31-21-22-6-11-27(29)30-20-22/h2-11,20H,12-19,21H2,1H3,(H,31,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	386	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL					Assay Description Displacement of [3H]-prazosin from rat brain alpha1 adrenergic receptor after 50 mins				Bioorg Med Chem 22: 1736-50 (2014) Article DOI: 10.1016/j.bmc.2014.01.016 BindingDB Entry DOI: 10.7270/Q2JW8HV0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50495573 (CHEMBL3113594) Show SMILES COc1ccc(cc1)-c1ccccc1N1CCN(CCOCCC(=O)NCc2ccc(F)nc2)CC1 Show InChI InChI=1S/C28H33FN4O3/c1-35-24-9-7-23(8-10-24)25-4-2-3-5-26(25)33-15-13-32(14-16-33)17-19-36-18-12-28(34)31-21-22-6-11-27(29)30-20-22/h2-11,20H,12-19,21H2,1H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	568	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor transfected in HEK293-EBNA cells after 120 mins				Bioorg Med Chem 22: 1736-50 (2014) Article DOI: 10.1016/j.bmc.2014.01.016 BindingDB Entry DOI: 10.7270/Q2JW8HV0
					More data for this Ligand-Target Pair