null

SMILES: COc1ccc(cc1)C1=Nn2c(SC1)nnc2-c1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=FMJACHMXQIMJIO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50496149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50496149 (CHEMBL3121755) Show SMILES COc1ccc(cc1)C1=Nn2c(SC1)nnc2-c1ccc(cc1)S(N)(=O)=O |t:9| Show InChI InChI=1S/C17H15N5O3S2/c1-25-13-6-2-11(3-7-13)15-10-26-17-20-19-16(22(17)21-15)12-4-8-14(9-5-12)27(18,23)24/h2-9H,10H2,1H3,(H2,18,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Inhibition of human transmembrane carbonic anhydrase 12 by stopped flow CO2 hydration assay				Bioorg Med Chem 22: 1873-82 (2014) Article DOI: 10.1016/j.bmc.2014.01.055 BindingDB Entry DOI: 10.7270/Q2W098W2
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50496149 (CHEMBL3121755) Show SMILES COc1ccc(cc1)C1=Nn2c(SC1)nnc2-c1ccc(cc1)S(N)(=O)=O |t:9| Show InChI InChI=1S/C17H15N5O3S2/c1-25-13-6-2-11(3-7-13)15-10-26-17-20-19-16(22(17)21-15)12-4-8-14(9-5-12)27(18,23)24/h2-9H,10H2,1H3,(H2,18,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Inhibition of human transmembrane carbonic anhydrase 9 by stopped flow CO2 hydration assay				Bioorg Med Chem 22: 1873-82 (2014) Article DOI: 10.1016/j.bmc.2014.01.055 BindingDB Entry DOI: 10.7270/Q2W098W2
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50496149 (CHEMBL3121755) Show SMILES COc1ccc(cc1)C1=Nn2c(SC1)nnc2-c1ccc(cc1)S(N)(=O)=O |t:9| Show InChI InChI=1S/C17H15N5O3S2/c1-25-13-6-2-11(3-7-13)15-10-26-17-20-19-16(22(17)21-15)12-4-8-14(9-5-12)27(18,23)24/h2-9H,10H2,1H3,(H2,18,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Inhibition of human cytosolic carbonic anhydrase 2 by stopped flow CO2 hydration assay				Bioorg Med Chem 22: 1873-82 (2014) Article DOI: 10.1016/j.bmc.2014.01.055 BindingDB Entry DOI: 10.7270/Q2W098W2
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50496149 (CHEMBL3121755) Show SMILES COc1ccc(cc1)C1=Nn2c(SC1)nnc2-c1ccc(cc1)S(N)(=O)=O |t:9| Show InChI InChI=1S/C17H15N5O3S2/c1-25-13-6-2-11(3-7-13)15-10-26-17-20-19-16(22(17)21-15)12-4-8-14(9-5-12)27(18,23)24/h2-9H,10H2,1H3,(H2,18,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Inhibition of human cytosolic carbonic anhydrase 1 by stopped flow CO2 hydration assay				Bioorg Med Chem 22: 1873-82 (2014) Article DOI: 10.1016/j.bmc.2014.01.055 BindingDB Entry DOI: 10.7270/Q2W098W2
					More data for this Ligand-Target Pair