null

SMILES: NS(=O)(=O)c1ccc(cc1)-c1nnc2SCC(=Nn12)c1ccc(Br)cc1

InChI Key: InChIKey=YTCSFDOWBQOSJI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50496154   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50496154 (CHEMBL3121758) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nnc2SCC(=Nn12)c1ccc(Br)cc1 |c:17| Show InChI InChI=1S/C16H12BrN5O2S2/c17-12-5-1-10(2-6-12)14-9-25-16-20-19-15(22(16)21-14)11-3-7-13(8-4-11)26(18,23)24/h1-8H,9H2,(H2,18,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Inhibition of human transmembrane carbonic anhydrase 12 by stopped flow CO2 hydration assay				Bioorg Med Chem 22: 1873-82 (2014) Article DOI: 10.1016/j.bmc.2014.01.055 BindingDB Entry DOI: 10.7270/Q2W098W2
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50496154 (CHEMBL3121758) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nnc2SCC(=Nn12)c1ccc(Br)cc1 |c:17| Show InChI InChI=1S/C16H12BrN5O2S2/c17-12-5-1-10(2-6-12)14-9-25-16-20-19-15(22(16)21-14)11-3-7-13(8-4-11)26(18,23)24/h1-8H,9H2,(H2,18,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Inhibition of human transmembrane carbonic anhydrase 9 by stopped flow CO2 hydration assay				Bioorg Med Chem 22: 1873-82 (2014) Article DOI: 10.1016/j.bmc.2014.01.055 BindingDB Entry DOI: 10.7270/Q2W098W2
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50496154 (CHEMBL3121758) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nnc2SCC(=Nn12)c1ccc(Br)cc1 |c:17| Show InChI InChI=1S/C16H12BrN5O2S2/c17-12-5-1-10(2-6-12)14-9-25-16-20-19-15(22(16)21-14)11-3-7-13(8-4-11)26(18,23)24/h1-8H,9H2,(H2,18,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Inhibition of human cytosolic carbonic anhydrase 2 by stopped flow CO2 hydration assay				Bioorg Med Chem 22: 1873-82 (2014) Article DOI: 10.1016/j.bmc.2014.01.055 BindingDB Entry DOI: 10.7270/Q2W098W2
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50496154 (CHEMBL3121758) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nnc2SCC(=Nn12)c1ccc(Br)cc1 |c:17| Show InChI InChI=1S/C16H12BrN5O2S2/c17-12-5-1-10(2-6-12)14-9-25-16-20-19-15(22(16)21-14)11-3-7-13(8-4-11)26(18,23)24/h1-8H,9H2,(H2,18,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kurukshetra University Curated by ChEMBL					Assay Description Inhibition of human cytosolic carbonic anhydrase 1 by stopped flow CO2 hydration assay				Bioorg Med Chem 22: 1873-82 (2014) Article DOI: 10.1016/j.bmc.2014.01.055 BindingDB Entry DOI: 10.7270/Q2W098W2
					More data for this Ligand-Target Pair