null
SMILES: Cc1ccc(cc1)C1=Nn2c(SC1)nnc2-c1ccc(cc1)S(N)(=O)=O
InChI Key: InChIKey=CJYRWDLBYJRULF-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM50496156 (CHEMBL3121754) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kurukshetra University Curated by ChEMBL | Assay Description Inhibition of human transmembrane carbonic anhydrase 12 by stopped flow CO2 hydration assay | Bioorg Med Chem 22: 1873-82 (2014) Article DOI: 10.1016/j.bmc.2014.01.055 BindingDB Entry DOI: 10.7270/Q2W098W2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM50496156 (CHEMBL3121754) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kurukshetra University Curated by ChEMBL | Assay Description Inhibition of human transmembrane carbonic anhydrase 9 by stopped flow CO2 hydration assay | Bioorg Med Chem 22: 1873-82 (2014) Article DOI: 10.1016/j.bmc.2014.01.055 BindingDB Entry DOI: 10.7270/Q2W098W2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50496156 (CHEMBL3121754) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 73 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kurukshetra University Curated by ChEMBL | Assay Description Inhibition of human cytosolic carbonic anhydrase 2 by stopped flow CO2 hydration assay | Bioorg Med Chem 22: 1873-82 (2014) Article DOI: 10.1016/j.bmc.2014.01.055 BindingDB Entry DOI: 10.7270/Q2W098W2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50496156 (CHEMBL3121754) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 292 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kurukshetra University Curated by ChEMBL | Assay Description Inhibition of human cytosolic carbonic anhydrase 1 by stopped flow CO2 hydration assay | Bioorg Med Chem 22: 1873-82 (2014) Article DOI: 10.1016/j.bmc.2014.01.055 BindingDB Entry DOI: 10.7270/Q2W098W2 | |||||||||||
More data for this Ligand-Target Pair |