BDBM50496414 CHEMBL3127411

SMILES: Fc1ccc(CN(C[C@@H]2CCC(=O)N2)S(=O)(=O)c2cccc(Cl)c2)cc1

InChI Key: InChIKey=ZRKHTEJYISNKOY-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50496414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50496414 (CHEMBL3127411) Show SMILES Fc1ccc(CN(C[C@@H]2CCC(=O)N2)S(=O)(=O)c2cccc(Cl)c2)cc1 |r| Show InChI InChI=1S/C18H18ClFN2O3S/c19-14-2-1-3-17(10-14)26(24,25)22(12-16-8-9-18(23)21-16)11-13-4-6-15(20)7-5-13/h1-7,10,16H,8-9,11-12H2,(H,21,23)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 ion channel expressed in CHO cells by patch clamp assay				Bioorg Med Chem Lett 24: 1269-73 (2014) Article DOI: 10.1016/j.bmcl.2014.01.067 BindingDB Entry DOI: 10.7270/Q2930X4D
					More data for this Ligand-Target Pair