BDBM50497099 CHEMBL3263459
SMILES: COc1ccc(CNC(=O)c2[nH]c3ccc(Cl)cc3c2S(=O)(=O)c2cc(C)cc(C)c2)cc1
InChI Key: InChIKey=JKGNOCZOVVBHFE-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50497099 (CHEMBL3263459) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of HIV1 wild-type reverse transcriptase K103N mutant using [3H]dTTP by scintillation counting | Eur J Med Chem 80: 101-11 (2014) Article DOI: 10.1016/j.ejmech.2014.04.027 BindingDB Entry DOI: 10.7270/Q2VM4G8G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50497099 (CHEMBL3263459) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of HIV1 wild-type reverse transcriptase using [3H]dTTP by scintillation counting | Eur J Med Chem 80: 101-11 (2014) Article DOI: 10.1016/j.ejmech.2014.04.027 BindingDB Entry DOI: 10.7270/Q2VM4G8G | |||||||||||
More data for this Ligand-Target Pair |