BDBM50497316 CHEMBL3356517

SMILES: CC(C)c1ccccc1-c1ncc(C)c(NC(C)(C)c2ccc(cc2)-n2ccnn2)n1

InChI Key: InChIKey=OALUVRRCKYSYHZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50497316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM50497316 (CHEMBL3356517) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NC(C)(C)c2ccc(cc2)-n2ccnn2)n1 Show InChI InChI=1S/C25H28N6/c1-17(2)21-8-6-7-9-22(21)24-26-16-18(3)23(28-24)29-25(4,5)19-10-12-20(13-11-19)31-15-14-27-30-31/h6-17H,1-5H3,(H,26,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay				J Med Chem 57: 8099-110 (2014) Article DOI: 10.1021/jm5010495 BindingDB Entry DOI: 10.7270/Q24X5BSH
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM50497316 (CHEMBL3356517) Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NC(C)(C)c2ccc(cc2)-n2ccnn2)n1 Show InChI InChI=1S/C25H28N6/c1-17(2)21-8-6-7-9-22(21)24-26-16-18(3)23(28-24)29-25(4,5)19-10-12-20(13-11-19)31-15-14-27-30-31/h6-17H,1-5H3,(H,26,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay				J Med Chem 57: 8099-110 (2014) Article DOI: 10.1021/jm5010495 BindingDB Entry DOI: 10.7270/Q24X5BSH
					More data for this Ligand-Target Pair