BDBM50497317 CHEMBL3188953

SMILES: Brc1ccccc1-c1nc(NCc2ccc(cc2)-c2cccnc2)c2ccccc2n1

InChI Key: InChIKey=ZYMZUOXPYVPRDR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50497317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM50497317 (CHEMBL3188953) Show SMILES Brc1ccccc1-c1nc(NCc2ccc(cc2)-c2cccnc2)c2ccccc2n1 Show InChI InChI=1S/C26H19BrN4/c27-23-9-3-1-7-21(23)26-30-24-10-4-2-8-22(24)25(31-26)29-16-18-11-13-19(14-12-18)20-6-5-15-28-17-20/h1-15,17H,16H2,(H,29,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay				J Med Chem 57: 8099-110 (2014) Article DOI: 10.1021/jm5010495 BindingDB Entry DOI: 10.7270/Q24X5BSH
					More data for this Ligand-Target Pair