BDBM50497340 CHEMBL3186327

SMILES: CC(C)c1ccccc1-c1nc(NCc2ccc(cc2)-c2cccnc2)c2ccccc2n1

InChI Key: InChIKey=ZUGPAPZFXDQYJW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50497340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM50497340 (CHEMBL3186327) Show SMILES CC(C)c1ccccc1-c1nc(NCc2ccc(cc2)-c2cccnc2)c2ccccc2n1 Show InChI InChI=1S/C29H26N4/c1-20(2)24-9-3-4-10-25(24)29-32-27-12-6-5-11-26(27)28(33-29)31-18-21-13-15-22(16-14-21)23-8-7-17-30-19-23/h3-17,19-20H,18H2,1-2H3,(H,31,32,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay				J Med Chem 57: 8099-110 (2014) Article DOI: 10.1021/jm5010495 BindingDB Entry DOI: 10.7270/Q24X5BSH
					More data for this Ligand-Target Pair