BDBM50497343 CHEMBL3189092

SMILES: Cc1cnc(nc1NCc1ccc(cc1)-n1ccnn1)-c1ccccc1C(F)F

InChI Key: InChIKey=FTVAQPNJOHGXJS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50497343   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM50497343 (CHEMBL3189092) Show SMILES Cc1cnc(nc1NCc1ccc(cc1)-n1ccnn1)-c1ccccc1C(F)F Show InChI InChI=1S/C21H18F2N6/c1-14-12-24-21(18-5-3-2-4-17(18)19(22)23)27-20(14)25-13-15-6-8-16(9-7-15)29-11-10-26-28-29/h2-12,19H,13H2,1H3,(H,24,25,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay				J Med Chem 57: 8099-110 (2014) Article DOI: 10.1021/jm5010495 BindingDB Entry DOI: 10.7270/Q24X5BSH
					More data for this Ligand-Target Pair