BDBM50497349 CHEMBL3183657

SMILES: CC(C)c1ccccc1-c1nc2CCCc2c(NCc2ccc(cc2)-c2cccnc2)n1

InChI Key: InChIKey=MYVXJHJCBXQWBE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50497349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM50497349 (CHEMBL3183657) Show SMILES CC(C)c1ccccc1-c1nc2CCCc2c(NCc2ccc(cc2)-c2cccnc2)n1 Show InChI InChI=1S/C28H28N4/c1-19(2)23-8-3-4-9-24(23)28-31-26-11-5-10-25(26)27(32-28)30-17-20-12-14-21(15-13-20)22-7-6-16-29-18-22/h3-4,6-9,12-16,18-19H,5,10-11,17H2,1-2H3,(H,30,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay				J Med Chem 57: 8099-110 (2014) Article DOI: 10.1021/jm5010495 BindingDB Entry DOI: 10.7270/Q24X5BSH
					More data for this Ligand-Target Pair