BDBM50497361 CHEMBL3356111

SMILES: FC(F)(F)c1ccccc1-c1nc(NCc2ccc(cc2)-c2ccncc2)c2ccccc2n1

InChI Key: InChIKey=OZHWJTKJRJQEKI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50497361   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM50497361 (CHEMBL3356111) Show SMILES FC(F)(F)c1ccccc1-c1nc(NCc2ccc(cc2)-c2ccncc2)c2ccccc2n1 Show InChI InChI=1S/C27H19F3N4/c28-27(29,30)23-7-3-1-5-21(23)26-33-24-8-4-2-6-22(24)25(34-26)32-17-18-9-11-19(12-10-18)20-13-15-31-16-14-20/h1-16H,17H2,(H,32,33,34)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay				J Med Chem 57: 8099-110 (2014) Article DOI: 10.1021/jm5010495 BindingDB Entry DOI: 10.7270/Q24X5BSH
					More data for this Ligand-Target Pair