BDBM50497363 CHEMBL3189120

SMILES: CSc1cnc(nc1NCc1ccc(cc1)-c1cccnc1)-c1ccccc1C(C)C

InChI Key: InChIKey=BCGFWIIBNQKEOS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50497363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human))	BDBM50497363 (CHEMBL3189120) Show SMILES CSc1cnc(nc1NCc1ccc(cc1)-c1cccnc1)-c1ccccc1C(C)C Show InChI InChI=1S/C26H26N4S/c1-18(2)22-8-4-5-9-23(22)25-29-17-24(31-3)26(30-25)28-15-19-10-12-20(13-11-19)21-7-6-14-27-16-21/h4-14,16-18H,15H2,1-3H3,(H,28,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay				J Med Chem 57: 8099-110 (2014) Article DOI: 10.1021/jm5010495 BindingDB Entry DOI: 10.7270/Q24X5BSH
					More data for this Ligand-Target Pair