BDBM50497388 CHEMBL3339137
SMILES: Fc1cccc(NC(=O)Nc2cc(nn2Cc2ccccc2)C2CC2(F)F)c1
InChI Key: InChIKey=TUGCMTGUHLKFST-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50497388 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50497388
(CHEMBL3339137)Show SMILES Fc1cccc(NC(=O)Nc2cc(nn2Cc2ccccc2)C2CC2(F)F)c1 Show InChI InChI=1S/C20H17F3N4O/c21-14-7-4-8-15(9-14)24-19(28)25-18-10-17(16-11-20(16,22)23)26-27(18)12-13-5-2-1-3-6-13/h1-10,16H,11-12H2,(H2,24,25,28) | Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 920 | n/a | n/a | n/a | n/a |
Northwest A&F University
Curated by ChEMBL
| Assay Description
Activation of GIRK1/4 (unknown origin) by thallium-flux based assay |
Bioorg Med Chem Lett 24: 5102-6 (2014)
Article DOI: 10.1016/j.bmcl.2014.08.061
BindingDB Entry DOI: 10.7270/Q2WD43JR |
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50497388
(CHEMBL3339137)Show SMILES Fc1cccc(NC(=O)Nc2cc(nn2Cc2ccccc2)C2CC2(F)F)c1 Show InChI InChI=1S/C20H17F3N4O/c21-14-7-4-8-15(9-14)24-19(28)25-18-10-17(16-11-20(16,22)23)26-27(18)12-13-5-2-1-3-6-13/h1-10,16H,11-12H2,(H2,24,25,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 730 | n/a | n/a | n/a | n/a |
Northwest A&F University
Curated by ChEMBL
| Assay Description
Activation of GIRK1/2 (unknown origin) by thallium-flux based assay |
Bioorg Med Chem Lett 24: 5102-6 (2014)
Article DOI: 10.1016/j.bmcl.2014.08.061
BindingDB Entry DOI: 10.7270/Q2WD43JR |
More data for this
Ligand-Target Pair | |
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