null

SMILES: CC1CC1c1cc(NC(=O)Nc2cccc(F)c2)n(CC(F)(F)F)n1

InChI Key: InChIKey=LKMCYAKQUCOEKN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50497391   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50497391 (CHEMBL3339147) Show SMILES CC1CC1c1cc(NC(=O)Nc2cccc(F)c2)n(CC(F)(F)F)n1 Show InChI InChI=1S/C16H16F4N4O/c1-9-5-12(9)13-7-14(24(23-13)8-16(18,19)20)22-15(25)21-11-4-2-3-10(17)6-11/h2-4,6-7,9,12H,5,8H2,1H3,(H2,21,22,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Northwest A&F University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) by thallium-flux based assay				Bioorg Med Chem Lett 24: 5102-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.061 BindingDB Entry DOI: 10.7270/Q2WD43JR
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50497391 (CHEMBL3339147) Show SMILES CC1CC1c1cc(NC(=O)Nc2cccc(F)c2)n(CC(F)(F)F)n1 Show InChI InChI=1S/C16H16F4N4O/c1-9-5-12(9)13-7-14(24(23-13)8-16(18,19)20)22-15(25)21-11-4-2-3-10(17)6-11/h2-4,6-7,9,12H,5,8H2,1H3,(H2,21,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Northwest A&F University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) by thallium-flux based assay				Bioorg Med Chem Lett 24: 5102-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.061 BindingDB Entry DOI: 10.7270/Q2WD43JR
					More data for this Ligand-Target Pair