BDBM50498400 CHEMBL3594201

SMILES: ONC(=O)CCCCCC(=O)NCc1cc(C(=O)NCc2ccccc2)c2ccccc2n1

InChI Key: InChIKey=APNNETGGCDTVPX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50498400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1/2 (Homo sapiens (Human))	BDBM50498400 (CHEMBL3594201) Show SMILES ONC(=O)CCCCCC(=O)NCc1cc(C(=O)NCc2ccccc2)c2ccccc2n1 Show InChI InChI=1S/C25H28N4O4/c30-23(13-5-2-6-14-24(31)29-33)26-17-19-15-21(20-11-7-8-12-22(20)28-19)25(32)27-16-18-9-3-1-4-10-18/h1,3-4,7-12,15,33H,2,5-6,13-14,16-17H2,(H,26,30)(H,27,32)(H,29,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	399	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HDAC1/2 in human HeLa cell nuclear extracts preincubated for 5 mins followed by substrate addition measured after 0.5 hrs by Color de L...				Bioorg Med Chem 23: 4364-4374 (2015) Article DOI: 10.1016/j.bmc.2015.06.024 BindingDB Entry DOI: 10.7270/Q2JQ1419
					More data for this Ligand-Target Pair