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SMILES: Cc1cc(cc(C)c1Oc1ccnc(n1)S(=O)(=O)CC(=O)Nc1ccc(cc1)[N+]([O-])=O)C#N

InChI Key: InChIKey=VBZNCCCGPNUSTO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50498739   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50498739
PNG
(CHEMBL3621395)
Show SMILES Cc1cc(cc(C)c1Oc1ccnc(n1)S(=O)(=O)CC(=O)Nc1ccc(cc1)[N+]([O-])=O)C#N
Show InChI InChI=1S/C21H17N5O6S/c1-13-9-15(11-22)10-14(2)20(13)32-19-7-8-23-21(25-19)33(30,31)12-18(27)24-16-3-5-17(6-4-16)26(28)29/h3-10H,12H2,1-2H3,(H,24,27)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 53n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase p66/p51 assessed as inhibition of biotin-dUTP incorporation using poly (rA)/oligo(dT)16 as template/primer i...

Eur J Med Chem 102: 215-22 (2015)


Article DOI: 10.1016/j.ejmech.2015.08.007
BindingDB Entry DOI: 10.7270/Q29Z97W1
More data for this
Ligand-Target Pair