null

SMILES: CCOC(=O)c1c(nc(=O)n(Cc2ccc(cc2)C(=O)\C=C(/O)C(O)=O)c1C(C)C)-c1ccc(F)cc1

InChI Key: InChIKey=UWSFDWYFZIVLSP-BKUYFWCQSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50498958   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50498958 (CHEMBL3735086) Show SMILES CCOC(=O)c1c(nc(=O)n(Cc2ccc(cc2)C(=O)\C=C(/O)C(O)=O)c1C(C)C)-c1ccc(F)cc1 Show InChI InChI=1S/C27H25FN2O7/c1-4-37-26(35)22-23(18-9-11-19(28)12-10-18)29-27(36)30(24(22)15(2)3)14-16-5-7-17(8-6-16)20(31)13-21(32)25(33)34/h5-13,15,32H,4,14H2,1-3H3,(H,33,34)/b21-13-	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Orl£ans et CNRS Curated by ChEMBL					Assay Description Inhibition of recombinant HIV-1 integrase 3'-processing activity expressed in Escherichia coli BL21(DE3) cells using 32P-labeled DNA substrate after ...				Eur J Med Chem 104: 127-38 (2015) Article DOI: 10.1016/j.ejmech.2015.09.015 BindingDB Entry DOI: 10.7270/Q2CR5XB5
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50498958 (CHEMBL3735086) Show SMILES CCOC(=O)c1c(nc(=O)n(Cc2ccc(cc2)C(=O)\C=C(/O)C(O)=O)c1C(C)C)-c1ccc(F)cc1 Show InChI InChI=1S/C27H25FN2O7/c1-4-37-26(35)22-23(18-9-11-19(28)12-10-18)29-27(36)30(24(22)15(2)3)14-16-5-7-17(8-6-16)20(31)13-21(32)25(33)34/h5-13,15,32H,4,14H2,1-3H3,(H,33,34)/b21-13-	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Orl£ans et CNRS Curated by ChEMBL					Assay Description Inhibition of recombinant HIV-1 integrase stand transfer activity expressed in Escherichia coli BL21(DE3) cells using 32P-labeled DNA substrate after...				Eur J Med Chem 104: 127-38 (2015) Article DOI: 10.1016/j.ejmech.2015.09.015 BindingDB Entry DOI: 10.7270/Q2CR5XB5
					More data for this Ligand-Target Pair