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SMILES: Oc1cc(O)c2cc(oc2c1)-c1ccc(O)c2ncccc12

InChI Key: InChIKey=JZVBDCRISWDLNE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50499094   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))		BDBM50499094
PNG
(CHEMBL3735557)
Show SMILES Oc1cc(O)c2cc(oc2c1)-c1ccc(O)c2ncccc12
Show InChI InChI=1S/C17H11NO4/c19-9-6-14(21)12-8-16(22-15(12)7-9)10-3-4-13(20)17-11(10)2-1-5-18-17/h1-8,19-21H
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KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.21E+3n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human PDE4D using 3H-cAMP as substrate after 15 mins by liquid scintillation counting analysis

J Med Chem 58: 8616-37 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01222
BindingDB Entry DOI: 10.7270/Q2GH9MZJ
More data for this
Ligand-Target Pair