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BDBM50499215 CHEMBL3735947

SMILES: [O-][N+](=O)c1ccc2CCC(CCc2c1)NCCCc1ccccc1

InChI Key: InChIKey=ZCIHOOYQUGPXHZ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50499215   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))
BDBM50499215
PNG
(CHEMBL3735947)
Show SMILES [O-][N+](=O)c1ccc2CCC(CCc2c1)NCCCc1ccccc1
Show InChI InChI=1S/C20H24N2O2/c23-22(24)20-13-10-17-8-11-19(12-9-18(17)15-20)21-14-4-7-16-5-2-1-3-6-16/h1-3,5-6,10,13,15,19,21H,4,7-9,11-12,14H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
1.60n/an/an/an/an/an/an/an/a



University Munster

Curated by ChEMBL


Assay Description
Displacement of [3H]ifenprodil from Glun2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by scintillation countin...


Bioorg Med Chem Lett 25: 5748-51 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.076
BindingDB Entry DOI: 10.7270/Q2639SQV
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))
BDBM50499215
PNG
(CHEMBL3735947)
Show SMILES [O-][N+](=O)c1ccc2CCC(CCc2c1)NCCCc1ccccc1
Show InChI InChI=1S/C20H24N2O2/c23-22(24)20-13-10-17-8-11-19(12-9-18(17)15-20)21-14-4-7-16-5-2-1-3-6-16/h1-3,5-6,10,13,15,19,21H,4,7-9,11-12,14H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
1.60n/an/an/an/an/an/an/an/a



Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL


Assay Description
Displacement of [3H]ifenprodil from human recombinant GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by ...


Bioorg Med Chem 28: (2020)

More data for this
Ligand-Target Pair
Sigma-1 receptor


(Cavia porcellus (Guinea pig))
BDBM50499215
PNG
(CHEMBL3735947)
Show SMILES [O-][N+](=O)c1ccc2CCC(CCc2c1)NCCCc1ccccc1
Show InChI InChI=1S/C20H24N2O2/c23-22(24)20-13-10-17-8-11-19(12-9-18(17)15-20)21-14-4-7-16-5-2-1-3-6-16/h1-3,5-6,10,13,15,19,21H,4,7-9,11-12,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
18n/an/an/an/an/an/an/an/a



University Munster

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-Pentazocine from sigma1 receptor in guniea pig brain cortex membranes by scintillation counting analysis


Bioorg Med Chem Lett 25: 5748-51 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.076
BindingDB Entry DOI: 10.7270/Q2639SQV
More data for this
Ligand-Target Pair