BDBM50499246 CHEMBL3735376

SMILES: Fc1ccc(cc1)-n1ncc2C[C@@]3(CN(CCC3=Cc12)S(=O)(=O)c1ccc(F)cc1)C(=O)c1ccccn1

InChI Key: InChIKey=AJJYMQGHGPINNM-NDEPHWFRSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50499246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50499246 (CHEMBL3735376) Show SMILES Fc1ccc(cc1)-n1ncc2C[C@@]3(CN(CCC3=Cc12)S(=O)(=O)c1ccc(F)cc1)C(=O)c1ccccn1 |r,c:19| Show InChI InChI=1S/C28H22F2N4O3S/c29-21-4-8-23(9-5-21)34-26-15-20-12-14-33(38(36,37)24-10-6-22(30)7-11-24)18-28(20,16-19(26)17-32-34)27(35)25-3-1-2-13-31-25/h1-11,13,15,17H,12,14,16,18H2/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Binding affinity to human recombinant glucocorticoid receptor by fluorescence polarization assay				Bioorg Med Chem Lett 25: 5720-5 (2015) Article DOI: 10.1016/j.bmcl.2015.10.097 BindingDB Entry DOI: 10.7270/Q2ST7STZ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50499246 (CHEMBL3735376) Show SMILES Fc1ccc(cc1)-n1ncc2C[C@@]3(CN(CCC3=Cc12)S(=O)(=O)c1ccc(F)cc1)C(=O)c1ccccn1 |r,c:19| Show InChI InChI=1S/C28H22F2N4O3S/c29-21-4-8-23(9-5-21)34-26-15-20-12-14-33(38(36,37)24-10-6-22(30)7-11-24)18-28(20,16-19(26)17-32-34)27(35)25-3-1-2-13-31-25/h1-11,13,15,17H,12,14,16,18H2/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human HepG2 cells assessed as inhibition of glucocorticoid-induced TAT activity after 24 hrs				Bioorg Med Chem Lett 25: 5720-5 (2015) Article DOI: 10.1016/j.bmcl.2015.10.097 BindingDB Entry DOI: 10.7270/Q2ST7STZ
					More data for this Ligand-Target Pair
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM50499246 (CHEMBL3735376) Show SMILES Fc1ccc(cc1)-n1ncc2C[C@@]3(CN(CCC3=Cc12)S(=O)(=O)c1ccc(F)cc1)C(=O)c1ccccn1 |r,c:19| Show InChI InChI=1S/C28H22F2N4O3S/c29-21-4-8-23(9-5-21)34-26-15-20-12-14-33(38(36,37)24-10-6-22(30)7-11-24)18-28(20,16-19(26)17-32-34)27(35)25-3-1-2-13-31-25/h1-11,13,15,17H,12,14,16,18H2/t28-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp technique				Bioorg Med Chem Lett 25: 5720-5 (2015) Article DOI: 10.1016/j.bmcl.2015.10.097 BindingDB Entry DOI: 10.7270/Q2ST7STZ
					More data for this Ligand-Target Pair