BDBM50499282 CHEMBL3735657

SMILES: COCCOc1ccc2C(=O)\C(Oc2c1C(C)N1CCNCC1)=C\c1n[nH]c2ncccc12

InChI Key: InChIKey=YMXYBWOECVATQB-ZHZULCJRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50499282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50499282 (CHEMBL3735657) Show SMILES COCCOc1ccc2C(=O)\C(Oc2c1C(C)N1CCNCC1)=C\c1n[nH]c2ncccc12 Show InChI InChI=1S/C24H27N5O4/c1-15(29-10-8-25-9-11-29)21-19(32-13-12-31-2)6-5-17-22(30)20(33-23(17)21)14-18-16-4-3-7-26-24(16)28-27-18/h3-7,14-15,25H,8-13H2,1-2H3,(H,26,27,28)/b20-14-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of PIM3 (unknown origin) using FL-Peptide 1 (5-FAM-AKRRRLSSLRA-COOH) substrate incubated for 2 hrs by electrophoretic mobility shift assay				Bioorg Med Chem Lett 25: 5687-93 (2015) Article DOI: 10.1016/j.bmcl.2015.10.098 BindingDB Entry DOI: 10.7270/Q2JD50SX
					More data for this Ligand-Target Pair