null

SMILES: COc1ccc(cc1)C1=Cc2ccc(F)cc2C(CC(=O)C(C)O)N1c1ccc(Cl)cc1

InChI Key: InChIKey=KQZOLAYKJPSVKV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50499566 (CHEMBL3742275) Show SMILES COc1ccc(cc1)C1=Cc2ccc(F)cc2C(CC(=O)C(C)O)N1c1ccc(Cl)cc1 |t:9| Show InChI InChI=1S/C26H23ClFNO3/c1-16(30)26(31)15-25-23-14-20(28)8-3-18(23)13-24(17-4-11-22(32-2)12-5-17)29(25)21-9-6-19(27)7-10-21/h3-14,16,25,30H,15H2,1-2H3	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Delhi Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase G140S mutant strand transfer activity preincubated for 30 mins followed by addition of FITC-labelled dsDNA for 1 hr by ...				ACS Med Chem Lett 6: 1065-70 (2015) Article DOI: 10.1021/acsmedchemlett.5b00230 BindingDB Entry DOI: 10.7270/Q2348PDM
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50499566 (CHEMBL3742275) Show SMILES COc1ccc(cc1)C1=Cc2ccc(F)cc2C(CC(=O)C(C)O)N1c1ccc(Cl)cc1 |t:9| Show InChI InChI=1S/C26H23ClFNO3/c1-16(30)26(31)15-25-23-14-20(28)8-3-18(23)13-24(17-4-11-22(32-2)12-5-17)29(25)21-9-6-19(27)7-10-21/h3-14,16,25,30H,15H2,1-2H3	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Delhi Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase strand transfer activity preincubated for 30 mins followed by addition of FITC-labelled dsDNA for 1 hr by microplate re...				ACS Med Chem Lett 6: 1065-70 (2015) Article DOI: 10.1021/acsmedchemlett.5b00230 BindingDB Entry DOI: 10.7270/Q2348PDM
					More data for this Ligand-Target Pair