BDBM50500027 CHEMBL3740074
SMILES: OC(=O)c1ccccc1NC(=O)c1ccc2C(=O)N(Cc3ccccc3)C(=O)c2c1
InChI Key: InChIKey=GQEVVWHZGOCRCN-UHFFFAOYSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 7 (Homo sapiens (Human)) | BDBM50500027 (CHEMBL3740074) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase-7 preincubated for 15 mins by stopped flow CO2 dehydration assay | Bioorg Med Chem 24: 20-5 (2016) Article DOI: 10.1016/j.bmc.2015.11.034 BindingDB Entry DOI: 10.7270/Q29K4F79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM50500027 (CHEMBL3740074) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase-12 preincubated for 15 mins by stopped flow CO2 dehydration assay | Bioorg Med Chem 24: 20-5 (2016) Article DOI: 10.1016/j.bmc.2015.11.034 BindingDB Entry DOI: 10.7270/Q29K4F79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50500027 (CHEMBL3740074) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 2.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase-1 preincubated for 15 mins by stopped flow CO2 dehydration assay | Bioorg Med Chem 24: 20-5 (2016) Article DOI: 10.1016/j.bmc.2015.11.034 BindingDB Entry DOI: 10.7270/Q29K4F79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 4 (Homo sapiens (Human)) | BDBM50500027 (CHEMBL3740074) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 7.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase-4 preincubated for 15 mins by stopped flow CO2 dehydration assay | Bioorg Med Chem 24: 20-5 (2016) Article DOI: 10.1016/j.bmc.2015.11.034 BindingDB Entry DOI: 10.7270/Q29K4F79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50500027 (CHEMBL3740074) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 dehydration assay | Bioorg Med Chem 24: 20-5 (2016) Article DOI: 10.1016/j.bmc.2015.11.034 BindingDB Entry DOI: 10.7270/Q29K4F79 | |||||||||||
More data for this Ligand-Target Pair |