BDBM50500088 CHEMBL3740144
SMILES: CN1CCN(Cc2ccc(NC(=O)Nc3ccc4ncnc(Nc5ccc(OCc6cccc(F)c6)c(Cl)c5)c4c3)cc2)CC1
InChI Key: InChIKey=VBIIJIMQUUULLK-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50500088 (CHEMBL3740144) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of VEGFR-2 (unknown origin) assessed as ATP level by luminescence analysis | Bioorg Med Chem 24: 179-90 (2016) Article DOI: 10.1016/j.bmc.2015.12.001 BindingDB Entry DOI: 10.7270/Q2SJ1PM0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50500088 (CHEMBL3740144) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of wild-type EGFR tyrosine kinase (unknown origin) assessed as ATP level by luminescence analysis | Bioorg Med Chem 24: 179-90 (2016) Article DOI: 10.1016/j.bmc.2015.12.001 BindingDB Entry DOI: 10.7270/Q2SJ1PM0 | |||||||||||
More data for this Ligand-Target Pair |