BDBM50500181 CHEMBL3676300

SMILES: C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1csc(n1)-c1c(F)cccc1F

InChI Key: InChIKey=YKTHPBIEPMMOPM-MJBXVCDLSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50500181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50500181 (CHEMBL3676300) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1csc(n1)-c1c(F)cccc1F Show InChI InChI=1S/C22H22F2N4OS/c1-12-7-13(9-14(25)8-12)15-5-6-26-10-18(15)27-21(29)19-11-30-22(28-19)20-16(23)3-2-4-17(20)24/h2-6,10-14H,7-9,25H2,1H3,(H,27,29)/t12-,13+,14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of PIM1 kinase (unknown origin) using NH2-AGAGRSRHSSYPAGT-OH as substrate by kinase-Glo assay				J Med Chem 58: 8373-86 (2015) Article DOI: 10.1021/acs.jmedchem.5b01275 BindingDB Entry DOI: 10.7270/Q2H41VGN
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50500181 (CHEMBL3676300) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1csc(n1)-c1c(F)cccc1F Show InChI InChI=1S/C22H22F2N4OS/c1-12-7-13(9-14(25)8-12)15-5-6-26-10-18(15)27-21(29)19-11-30-22(28-19)20-16(23)3-2-4-17(20)24/h2-6,10-14H,7-9,25H2,1H3,(H,27,29)/t12-,13+,14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of PIM3 kinase (unknown origin) using NH2-AGAGRSRHSSYPAGT-OH as substrate by kinase-Glo assay				J Med Chem 58: 8373-86 (2015) Article DOI: 10.1021/acs.jmedchem.5b01275 BindingDB Entry DOI: 10.7270/Q2H41VGN
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50500181 (CHEMBL3676300) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1csc(n1)-c1c(F)cccc1F Show InChI InChI=1S/C22H22F2N4OS/c1-12-7-13(9-14(25)8-12)15-5-6-26-10-18(15)27-21(29)19-11-30-22(28-19)20-16(23)3-2-4-17(20)24/h2-6,10-14H,7-9,25H2,1H3,(H,27,29)/t12-,13+,14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of PIM2 kinase (unknown origin) using NH2-AGAGRSRHSSYPAGT-OH as substrate by kinase-Glo assay				J Med Chem 58: 8373-86 (2015) Article DOI: 10.1021/acs.jmedchem.5b01275 BindingDB Entry DOI: 10.7270/Q2H41VGN
					More data for this Ligand-Target Pair