null

SMILES: C[C@](O)(c1cccc(c1)-c1cccc2cc(sc12)[C@H](NS(=O)(=O)C1CC1)c1ccccc1Cl)C(F)(F)F

InChI Key: InChIKey=IIJVSKWKBSNBCJ-RSXGOPAZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50500214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50500214 (CHEMBL3746954) Show SMILES C[C@](O)(c1cccc(c1)-c1cccc2cc(sc12)[C@H](NS(=O)(=O)C1CC1)c1ccccc1Cl)C(F)(F)F |r| Show InChI InChI=1S/C27H23ClF3NO3S2/c1-26(33,27(29,30)31)18-8-4-6-16(14-18)20-10-5-7-17-15-23(36-25(17)20)24(21-9-2-3-11-22(21)28)32-37(34,35)19-12-13-19/h2-11,14-15,19,24,32-33H,12-13H2,1H3/t24-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Binding affinity to human GKRP by surface plasmon resonance analysis				J Med Chem 58: 9663-79 (2015) Article DOI: 10.1021/acs.jmedchem.5b01367 BindingDB Entry DOI: 10.7270/Q27M0BZP
					More data for this Ligand-Target Pair
Glucokinase regulatory protein (Mus musculus)	BDBM50500214 (CHEMBL3746954) Show SMILES C[C@](O)(c1cccc(c1)-c1cccc2cc(sc12)[C@H](NS(=O)(=O)C1CC1)c1ccccc1Cl)C(F)(F)F |r| Show InChI InChI=1S/C27H23ClF3NO3S2/c1-26(33,27(29,30)31)18-8-4-6-16(14-18)20-10-5-7-17-15-23(36-25(17)20)24(21-9-2-3-11-22(21)28)32-37(34,35)19-12-13-19/h2-11,14-15,19,24,32-33H,12-13H2,1H3/t24-,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of glucokinase-GKRP binding interaction in mouse hepatocytes assessed as induction of glucokinase translocation				J Med Chem 58: 9663-79 (2015) Article DOI: 10.1021/acs.jmedchem.5b01367 BindingDB Entry DOI: 10.7270/Q27M0BZP
					More data for this Ligand-Target Pair
Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50500214 (CHEMBL3746954) Show SMILES C[C@](O)(c1cccc(c1)-c1cccc2cc(sc12)[C@H](NS(=O)(=O)C1CC1)c1ccccc1Cl)C(F)(F)F |r| Show InChI InChI=1S/C27H23ClF3NO3S2/c1-26(33,27(29,30)31)18-8-4-6-16(14-18)20-10-5-7-17-15-23(36-25(17)20)24(21-9-2-3-11-22(21)28)32-37(34,35)19-12-13-19/h2-11,14-15,19,24,32-33H,12-13H2,1H3/t24-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Binding affinity to human biotinylated AviTag GKRP assessed as inhibition of protein interaction with fluorescein tagged human glucokinase by AlphaSc...				J Med Chem 58: 9663-79 (2015) Article DOI: 10.1021/acs.jmedchem.5b01367 BindingDB Entry DOI: 10.7270/Q27M0BZP
					More data for this Ligand-Target Pair