null

SMILES: Clc1ccccc1[C@@H](NS(=O)(=O)c1ccc2OCCOc2c1)c1cc2ccccc2s1

InChI Key: InChIKey=LBZRWOSPKDKIOG-HSZRJFAPSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase regulatory protein (Mus musculus)	BDBM50500215 (CHEMBL3746762) Show SMILES Clc1ccccc1[C@@H](NS(=O)(=O)c1ccc2OCCOc2c1)c1cc2ccccc2s1 |r| Show InChI InChI=1S/C23H18ClNO4S2/c24-18-7-3-2-6-17(18)23(22-13-15-5-1-4-8-21(15)30-22)25-31(26,27)16-9-10-19-20(14-16)29-12-11-28-19/h1-10,13-14,23,25H,11-12H2/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of glucokinase-GKRP binding interaction in mouse hepatocytes assessed as induction of glucokinase translocation				J Med Chem 58: 9663-79 (2015) Article DOI: 10.1021/acs.jmedchem.5b01367 BindingDB Entry DOI: 10.7270/Q27M0BZP
					More data for this Ligand-Target Pair
Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50500215 (CHEMBL3746762) Show SMILES Clc1ccccc1[C@@H](NS(=O)(=O)c1ccc2OCCOc2c1)c1cc2ccccc2s1 |r| Show InChI InChI=1S/C23H18ClNO4S2/c24-18-7-3-2-6-17(18)23(22-13-15-5-1-4-8-21(15)30-22)25-31(26,27)16-9-10-19-20(14-16)29-12-11-28-19/h1-10,13-14,23,25H,11-12H2/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Binding affinity to human biotinylated AviTag GKRP assessed as inhibition of protein interaction with fluorescein tagged human glucokinase by AlphaSc...				J Med Chem 58: 9663-79 (2015) Article DOI: 10.1021/acs.jmedchem.5b01367 BindingDB Entry DOI: 10.7270/Q27M0BZP
					More data for this Ligand-Target Pair