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SMILES: COc1ccc(cc1)-c1nc(cc2c3ccccc3[nH]c12)C(=O)NCCCCC(=O)NO

InChI Key: InChIKey=LCLQQZKLHHICAG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500242   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10


(Homo sapiens (Human))		BDBM50500242
PNG
(CHEMBL3745844)
Show SMILES COc1ccc(cc1)-c1nc(cc2c3ccccc3[nH]c12)C(=O)NCCCCC(=O)NO
Show InChI InChI=1S/C24H24N4O4/c1-32-16-11-9-15(10-12-16)22-23-18(17-6-2-3-7-19(17)26-23)14-20(27-22)24(30)25-13-5-4-8-21(29)28-31/h2-3,6-7,9-12,14,26,31H,4-5,8,13H2,1H3,(H,25,30)(H,28,29)
PDB

UniProtKB/SwissProt

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GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 810n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis

J Med Chem 39: 817-25 (1996)


Article DOI: 10.1021/jm9506884
BindingDB Entry DOI: 10.7270/Q2028VK9
More data for this
Ligand-Target Pair