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BDBM50500308 CHEMBL3747091

SMILES: Cc1cc2cc(C)ccc2n1-c1nc2CCNCc2c(NCc2ccccc2)n1

InChI Key: InChIKey=ZOVFVICKRMORLF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500308   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transitional endoplasmic reticulum ATPase


(Homo sapiens (Human))		BDBM50500308
PNG
(CHEMBL3747091)
Show SMILES Cc1cc2cc(C)ccc2n1-c1nc2CCNCc2c(NCc2ccccc2)n1
Show InChI InChI=1S/C24H25N5/c1-16-8-9-22-19(12-16)13-17(2)29(22)24-27-21-10-11-25-15-20(21)23(28-24)26-14-18-6-4-3-5-7-18/h3-9,12-13,25H,10-11,14-15H2,1-2H3,(H,26,27,28)
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Cleave Biosciences Inc.

Curated by ChEMBL


Assay Description
Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assay

J Med Chem 58: 9480-97 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01346
BindingDB Entry DOI: 10.7270/Q2KW5K2P
More data for this
Ligand-Target Pair