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SMILES: FC1(CN2CCC1CC2)c1cn(nn1)-c1ccc(Br)cc1

InChI Key: InChIKey=FVZOEYTXZGRKAW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500418   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Rattus norvegicus (Rat))		BDBM50500418
PNG
(CHEMBL3746699)
Show SMILES FC1(CN2CCC1CC2)c1cn(nn1)-c1ccc(Br)cc1 |THB:0:1:5.4:7.8,9:1:5.4:7.8,(1.3,.14,;.25,-.49,;1.76,-2.89,;-.88,-3.54,;.22,-2.89,;.22,-1.61,;-.88,-.99,;-1.97,-1.61,;-1.97,-2.89,;-1.1,.29,;-2.49,-.34,;-3.52,.81,;-2.74,2.14,;-1.23,1.81,;-5.05,.66,;-5.79,-.69,;-7.33,-.73,;-8.13,.58,;-9.37,.55,;-7.39,1.94,;-5.85,1.98,)|
Show InChI InChI=1S/C15H16BrFN4/c16-12-1-3-13(4-2-12)21-9-14(18-19-21)15(17)10-20-7-5-11(15)6-8-20/h1-4,9,11H,5-8,10H2
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PC cid
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Article
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 150n/an/an/an/an/an/an/an/a



Universite Orleans

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nAchR in rat frontal cortices

Eur J Med Chem 107: 153-64 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.001
BindingDB Entry DOI: 10.7270/Q2TF01CW
More data for this
Ligand-Target Pair