BDBM50500873 CHEMBL3798644

SMILES: Cc1ccc(cc1)\N=c1/c2ccc(C)cc2n(C(=O)c2ccc(cc2)C(C)(C)C)c2c(O)c(O)c(O)cc12

InChI Key: InChIKey=OIVMGNAHDAEBBY-MUGXBBEHSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50500873   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50500873 (CHEMBL3798644) Show SMILES Cc1ccc(cc1)\N=c1/c2ccc(C)cc2n(C(=O)c2ccc(cc2)C(C)(C)C)c2c(O)c(O)c(O)cc12 Show InChI InChI=1S/C32H30N2O4/c1-18-6-13-22(14-7-18)33-27-23-15-8-19(2)16-25(23)34(28-24(27)17-26(35)29(36)30(28)37)31(38)20-9-11-21(12-10-20)32(3,4)5/h6-17,35-37H,1-5H3/b33-27+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	207	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Displacement of FAM-Bid peptide from N-terminal 8x His-tagged Bcl-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by fluore...				J Med Chem 59: 3152-62 (2016) Article DOI: 10.1021/acs.jmedchem.5b01913 BindingDB Entry DOI: 10.7270/Q2S75KBK
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50500873 (CHEMBL3798644) Show SMILES Cc1ccc(cc1)\N=c1/c2ccc(C)cc2n(C(=O)c2ccc(cc2)C(C)(C)C)c2c(O)c(O)c(O)cc12 Show InChI InChI=1S/C32H30N2O4/c1-18-6-13-22(14-7-18)33-27-23-15-8-19(2)16-25(23)34(28-24(27)17-26(35)29(36)30(28)37)31(38)20-9-11-21(12-10-20)32(3,4)5/h6-17,35-37H,1-5H3/b33-27+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	247	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Displacement of FAM-Bid peptide from N-terminal 8x His-tagged MCl-1 (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by fluore...				J Med Chem 59: 3152-62 (2016) Article DOI: 10.1021/acs.jmedchem.5b01913 BindingDB Entry DOI: 10.7270/Q2S75KBK
					More data for this Ligand-Target Pair
MDM2-MDMX (Homo sapiens (Human))	BDBM50500873 (CHEMBL3798644) Show SMILES Cc1ccc(cc1)\N=c1/c2ccc(C)cc2n(C(=O)c2ccc(cc2)C(C)(C)C)c2c(O)c(O)c(O)cc12 Show InChI InChI=1S/C32H30N2O4/c1-18-6-13-22(14-7-18)33-27-23-15-8-19(2)16-25(23)34(28-24(27)17-26(35)29(36)30(28)37)31(38)20-9-11-21(12-10-20)32(3,4)5/h6-17,35-37H,1-5H3/b33-27+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.43E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Displacement of FAM-p53TAD peptide from N-terminal 8x His-tagged human MDM2 (25 to 108 residues) expressed in Escherichia coli BL21 (DE3) after 30 mi...				J Med Chem 59: 3152-62 (2016) Article DOI: 10.1021/acs.jmedchem.5b01913 BindingDB Entry DOI: 10.7270/Q2S75KBK
					More data for this Ligand-Target Pair