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BDBM50500899 CHEMBL3798941

SMILES: OC(=O)C(F)(F)F.Clc1ccc(CNc2ccnc(n2)N2CCC3(CCN(C3)C(=O)C3CCNC3)CC2)c(Cl)c1

InChI Key: InChIKey=DAGYVHTXPPVTTM-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500899   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50500899
PNG
(CHEMBL3798941)
Show SMILES OC(=O)C(F)(F)F.Clc1ccc(CNc2ccnc(n2)N2CCC3(CCN(C3)C(=O)C3CCNC3)CC2)c(Cl)c1
Show InChI InChI=1S/C24H30Cl2N6O.C2HF3O2/c25-19-2-1-17(20(26)13-19)15-29-21-4-9-28-23(30-21)31-10-5-24(6-11-31)7-12-32(16-24)22(33)18-3-8-27-14-18;3-2(4,5)1(6)7/h1-2,4,9,13,18,27H,3,5-8,10-12,14-16H2,(H,28,29,30);(H,6,7)
UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
 50n/an/an/an/an/an/an/an/a



GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL


Assay Description
Displacement of [125I]-TARC from human recombinant CCR4 expressed in CHO cell membranes by scintillation counting method

Eur J Med Chem 115: 14-25 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.058
BindingDB Entry DOI: 10.7270/Q24J0J4S
More data for this
Ligand-Target Pair