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BDBM50500905 CHEMBL3798539

SMILES: Clc1ccc(CNc2ccnc(n2)N2CCC3(CCN(C3)C(=O)c3ccccn3)CC2)c(Cl)c1

InChI Key: InChIKey=YYRRYWWMNLUWON-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500905   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50500905
PNG
(CHEMBL3798539)
Show SMILES Clc1ccc(CNc2ccnc(n2)N2CCC3(CCN(C3)C(=O)c3ccccn3)CC2)c(Cl)c1
Show InChI InChI=1S/C25H26Cl2N6O/c26-19-5-4-18(20(27)15-19)16-30-22-6-11-29-24(31-22)32-12-7-25(8-13-32)9-14-33(17-25)23(34)21-3-1-2-10-28-21/h1-6,10-11,15H,7-9,12-14,16-17H2,(H,29,30,31)
UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
 100n/an/an/an/an/an/an/an/a



GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL


Assay Description
Displacement of [125I]-TARC from human recombinant CCR4 expressed in CHO cell membranes by scintillation counting method

Eur J Med Chem 115: 14-25 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.058
BindingDB Entry DOI: 10.7270/Q24J0J4S
More data for this
Ligand-Target Pair