BDBM50501702 CHEMBL4101195

SMILES: COc1ccc(cc1OC)C1CC(=NN1C(C)=O)c1c(C)oc2c(OC)c3occc3c(OC)c2c1=O

InChI Key: InChIKey=XUJXJGOYKOTUOC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50501702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 11/12/13/14 (Homo sapiens (Human))	BDBM50501702 (CHEMBL4101195) Show SMILES COc1ccc(cc1OC)C1CC(=NN1C(C)=O)c1c(C)oc2c(OC)c3occc3c(OC)c2c1=O |c:13| Show InChI InChI=1S/C27H26N2O8/c1-13-21(23(31)22-24(34-5)16-9-10-36-25(16)27(35-6)26(22)37-13)17-12-18(29(28-17)14(2)30)15-7-8-19(32-3)20(11-15)33-4/h7-11,18H,12H2,1-6H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of p38 MAPK (unknown origin) using ATF2 as substrate measured after 15 by ELISA				Bioorg Med Chem 25: 2423-2436 (2017) Article DOI: 10.1016/j.bmc.2017.02.065 BindingDB Entry DOI: 10.7270/Q29026TD
					More data for this Ligand-Target Pair