null
SMILES: COc1cc(ccc1O[C@@H](C)COc1cccc(c1)-n1ccnc1C1CC1)C#N
InChI Key: InChIKey=YZFFTLDUCWKOOJ-INIZCTEOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50502493![]() (CHEMBL4558383 | US11834430, Compound 81) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50502493![]() (CHEMBL4558383 | US11834430, Compound 81) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s... | ACS Med Chem Lett 10: 1024-1025 (2019) Article DOI: 10.1021/acsmedchemlett.9b00269 BindingDB Entry DOI: 10.7270/Q2FN19F4 | |||||||||||
More data for this Ligand-Target Pair |