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SMILES: Nc1ccc(\C=C\c2ccc(O)c(c2)-c2ccccn2)cc1

InChI Key: InChIKey=AMBKOZUCUQKTRV-SNAWJCMRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50503632   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))		BDBM50503632
PNG
(CHEMBL4520476)
Show SMILES Nc1ccc(\C=C\c2ccc(O)c(c2)-c2ccccn2)cc1
Show InChI InChI=1S/C19H16N2O/c20-16-9-6-14(7-10-16)4-5-15-8-11-19(22)17(13-15)18-3-1-2-12-21-18/h1-13,22H,20H2/b5-4+
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n/an/a 3.57E+3n/an/an/an/an/an/a



Xinxiang Medical University

Curated by ChEMBL


Assay Description
Inhibition of full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 peptide as substrate after 30 mins by fluoresce...

Bioorg Med Chem 26: 6000-6014 (2018)


Article DOI: 10.1016/j.bmc.2018.10.037
More data for this
Ligand-Target Pair