null

SMILES: ClC1=C(NCc2cn(Cc3ccccc3C#N)nn2)C(=O)c2ncccc2C1=O

InChI Key: InChIKey=CTGWNRFIOQUHLP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50504276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
M-phase inducer phosphatase 3 (Homo sapiens (Human))	BDBM50504276 (CHEMBL4466461) Show SMILES ClC1=C(NCc2cn(Cc3ccccc3C#N)nn2)C(=O)c2ncccc2C1=O |c:1| Show InChI InChI=1S/C20H13ClN6O2/c21-16-18(20(29)17-15(19(16)28)6-3-7-23-17)24-9-14-11-27(26-25-14)10-13-5-2-1-4-12(13)8-22/h1-7,11,24H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of recombinant human Cdc25C using OMFP as substrate preincubated for 5 to 8 mins and measured every 5 mins 60 mins by fluorescence based a...				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111696 BindingDB Entry DOI: 10.7270/Q21R6TS1
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50504276 (CHEMBL4466461) Show SMILES ClC1=C(NCc2cn(Cc3ccccc3C#N)nn2)C(=O)c2ncccc2C1=O |c:1| Show InChI InChI=1S/C20H13ClN6O2/c21-16-18(20(29)17-15(19(16)28)6-3-7-23-17)24-9-14-11-27(26-25-14)10-13-5-2-1-4-12(13)8-22/h1-7,11,24H,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of recombinant human Cdc25B using OMFP as substrate preincubated for 5 to 8 mins and measured every 5 mins 60 mins by fluorescence based a...				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111696 BindingDB Entry DOI: 10.7270/Q21R6TS1
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 1 (Homo sapiens (Human))	BDBM50504276 (CHEMBL4466461) Show SMILES ClC1=C(NCc2cn(Cc3ccccc3C#N)nn2)C(=O)c2ncccc2C1=O |c:1| Show InChI InChI=1S/C20H13ClN6O2/c21-16-18(20(29)17-15(19(16)28)6-3-7-23-17)24-9-14-11-27(26-25-14)10-13-5-2-1-4-12(13)8-22/h1-7,11,24H,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of recombinant human Cdc25A using OMFP as substrate preincubated for 5 to 8 mins and measured every 5 mins 60 mins by fluorescence based a...				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111696 BindingDB Entry DOI: 10.7270/Q21R6TS1
					More data for this Ligand-Target Pair