| Reaction Details |
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 | Report a problem with these data |
| Target | M-phase inducer phosphatase 3 |
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| Ligand | BDBM50504276 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1814178 (CHEMBL4313752) |
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| IC50 | 420±n/a nM |
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| Citation |  Jing, L; Wu, G; Hao, X; Olotu, FA; Kang, D; Chen, CH; Lee, KH; Soliman, MES; Liu, X; Song, Y; Zhan, P Identification of highly potent and selective Cdc25 protein phosphatases inhibitors from miniaturization click-chemistry-based combinatorial libraries. Eur J Med Chem183:0 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| M-phase inducer phosphatase 3 |
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| Name: | M-phase inducer phosphatase 3 |
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| Synonyms: | CDC25C | Dual specificity phosphatase Cdc25C | M-phase inducer phosphatase 3 | MPIP3_HUMAN |
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| Type: | Substrate |
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| Mol. Mass.: | 53366.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30307 |
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| Residue: | 473 |
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| Sequence: | MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL
SILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMK
CSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNP
NLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDK
VKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQ
DLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKK
PIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFF
PEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP
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| BDBM50504276 |
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| n/a |
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| Name | BDBM50504276 |
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| Synonyms: | CHEMBL4466461 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H13ClN6O2 |
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| Mol. Mass. | 404.809 |
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| SMILES | ClC1=C(NCc2cn(Cc3ccccc3C#N)nn2)C(=O)c2ncccc2C1=O |c:1| |
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| Structure | 
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