BDBM50505147 CHEMBL4451442

SMILES: Clc1ccc(cc1)N1CCN(CC1)C(=O)C(=O)Nc1ccc2[nH]c(=O)oc2c1

InChI Key: InChIKey=RKQPOJCTQMJIGR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50505147 (CHEMBL4451442) Show SMILES Clc1ccc(cc1)N1CCN(CC1)C(=O)C(=O)Nc1ccc2[nH]c(=O)oc2c1 Show InChI InChI=1S/C19H17ClN4O4/c20-12-1-4-14(5-2-12)23-7-9-24(10-8-23)18(26)17(25)21-13-3-6-15-16(11-13)28-19(27)22-15/h1-6,11H,7-10H2,(H,21,25)(H,22,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-ifenprodil from NR2B receptor in rat brain cerebral cortex membranes incubated for 120 mins by liquid scintillation counting met...				Bioorg Med Chem Lett 29: 1143-1147 (2019) Article DOI: 10.1016/j.bmcl.2019.02.017
					More data for this Ligand-Target Pair
Ionotropic glutamate receptor NMDA1/2B (Mus musculus)	BDBM50505147 (CHEMBL4451442) Show SMILES Clc1ccc(cc1)N1CCN(CC1)C(=O)C(=O)Nc1ccc2[nH]c(=O)oc2c1 Show InChI InChI=1S/C19H17ClN4O4/c20-12-1-4-14(5-2-12)23-7-9-24(10-8-23)18(26)17(25)21-13-3-6-15-16(11-13)28-19(27)22-15/h1-6,11H,7-10H2,(H,21,25)(H,22,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at mouse NR2B receptor expressed in HEK293 cells co-expressing NR1 subunit assessed as reduction in glutamic acid/glycine-induced...				Bioorg Med Chem Lett 29: 1143-1147 (2019) Article DOI: 10.1016/j.bmcl.2019.02.017
					More data for this Ligand-Target Pair