BDBM50505784 CHEMBL4464888

SMILES: COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccc(F)c(c1)N1CCS(=O)(=O)CC1

InChI Key: InChIKey=XLVXVPQDGQGCDE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505784 (CHEMBL4464888) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccc(F)c(c1)N1CCS(=O)(=O)CC1 Show InChI InChI=1S/C25H26FN3O4S2/c1-33-19-5-2-17(3-6-19)24-20-9-13-34-23(20)8-10-29(24)25(30)27-18-4-7-21(26)22(16-18)28-11-14-35(31,32)15-12-28/h2-7,9,13,16,24H,8,10-12,14-15H2,1H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382
					More data for this Ligand-Target Pair