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BDBM50505792 CHEMBL4471875

SMILES: COc1ccc(cc1)C1N(CCc2sccc12)C(=S)Nc1cc(OC)cc(OC)c1

InChI Key: InChIKey=LMRGYZVUBRTRHS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505792   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lutropin-choriogonadotropic hormone receptor


(Homo sapiens (Human))		BDBM50505792
PNG
(CHEMBL4471875)
Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=S)Nc1cc(OC)cc(OC)c1
Show InChI InChI=1S/C23H24N2O3S2/c1-26-17-6-4-15(5-7-17)22-20-9-11-30-21(20)8-10-25(22)23(29)24-16-12-18(27-2)14-19(13-16)28-3/h4-7,9,11-14,22H,8,10H2,1-3H3,(H,24,29)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.32E+3n/an/an/an/an/an/a



Bayer AG

Curated by ChEMBL


Assay Description
Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...

J Med Chem 62: 10321-10341 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01382
More data for this
Ligand-Target Pair