BDBM50505794 CHEMBL4456365

SMILES: COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccc(F)c(c1)C(N)=O

InChI Key: InChIKey=OMQYIPQXWHTTIR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505794   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505794 (CHEMBL4456365) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccc(F)c(c1)C(N)=O Show InChI InChI=1S/C22H20FN3O3S/c1-29-15-5-2-13(3-6-15)20-16-9-11-30-19(16)8-10-26(20)22(28)25-14-4-7-18(23)17(12-14)21(24)27/h2-7,9,11-12,20H,8,10H2,1H3,(H2,24,27)(H,25,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382
					More data for this Ligand-Target Pair