BDBM50505800 CHEMBL4588196

SMILES: Fc1cccc(c1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=XKGDBADCUICCEX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505800   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505800 (CHEMBL4588196) Show SMILES Fc1cccc(c1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C20H15Cl2FN2OS/c21-13-9-14(22)11-16(10-13)24-20(26)25-6-4-18-17(5-7-27-18)19(25)12-2-1-3-15(23)8-12/h1-3,5,7-11,19H,4,6H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382
					More data for this Ligand-Target Pair