BDBM50505808 CHEMBL4464604

SMILES: Fc1ccc(cc1F)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=RQUKUFPLLNLMTE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505808   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505808 (CHEMBL4464604) Show SMILES Fc1ccc(cc1F)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C20H14Cl2F2N2OS/c21-12-8-13(22)10-14(9-12)25-20(27)26-5-3-18-15(4-6-28-18)19(26)11-1-2-16(23)17(24)7-11/h1-2,4,6-10,19H,3,5H2,(H,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382
					More data for this Ligand-Target Pair