BDBM50505809 CHEMBL4460075

SMILES: Fc1ccc(NC(=O)N2CCc3sccc3C2c2ccc(Cl)cc2)cc1OC(F)(F)F

InChI Key: InChIKey=QTHWKVSMFPMGTR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505809 (CHEMBL4460075) Show SMILES Fc1ccc(NC(=O)N2CCc3sccc3C2c2ccc(Cl)cc2)cc1OC(F)(F)F Show InChI InChI=1S/C21H15ClF4N2O2S/c22-13-3-1-12(2-4-13)19-15-8-10-31-18(15)7-9-28(19)20(29)27-14-5-6-16(23)17(11-14)30-21(24,25)26/h1-6,8,10-11,19H,7,9H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382
					More data for this Ligand-Target Pair